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The classic of the weekend was Nacional – Millonarios. Nacional, winner of both legs of the Copa Mustang last year, was not able to beat their Bogotá rivals. The final score, 1 – 1, was better for the green/whiteteam from Medellín. They climbed two places to position 16, while the draw made Millonarios drop on place. They now hold the 8th postion.
| Results | Mustang I 2008 | |||||
| Huila | 1-1 | Medellín | 1 | La Equidad | ||
| Nacional | 1-1 | Millonarios | 2 | Santa Fe | ||
| Santa Fe | 3-0 | Envigado | 3 | Medellín | ||
| Caldas | 2-0 | Bucaramanga | 4 | Caldas | ||
| Cúcuta | 4-3 | Quindío | 5 | América | ||
| Junior | 1-0 | Pereira | 6 | Envigado | ||
| América | 3-1 | Tolima | 7 | Cali | ||
| Pasto | 1-2 | Equidad | 8 | Millionarios | ||
| Chicó FC | 0-0 | Cali | 9 | Cúcuta | ||
| 10 | Chicó | |||||
| 11 | Quindío | |||||
| 12 | Bucaramanga | |||||
| 13 | Huila | |||||
| 14 | Nacional | |||||
| 15 | Pasto | |||||
| 16 | Tolima | |||||
| 17 | Pereira | |||||
| 18 | Junior |
