According to police, two men arrived on motorcycle and left an explosive package close to a military police checkpoint. However, the explosion did not cause casualties among the military personnel, instead it wounded two civilians.
According to a local Huila newspaper, the two men fired warning shots into the air and ordered civilians in the area to leave before detonating the bomb.
The two wounded civilians were being treated at a local hospital as of Friday morning.
Authorities did not speculate on the background of the perpetrators.
Neiva, located in the south-central Huila department, has in the recent past been hit by attacks from FARC rebels. The city sees the presence of several FARC units, among them the urban Manuelita Saenz Company.